HIV-1 Variation Diminishes CD4 T Lymphocyte Recognition
نویسندگان
چکیده
منابع مشابه
HIV-1 Variation Diminishes CD4 T Lymphocyte Recognition
Effective long-term antiviral immunity requires specific cytotoxic T lymphocytes and CD4(+) T lymphocyte help. Failure of these helper responses can be a principle cause of viral persistence. We sought evidence that variation in HIV-1 CD4(+) T helper epitopes might contribute to this phenomenon. To determine this, we assayed fresh peripheral blood mononuclear cells from 43 asymptomatic HIV-1(+)...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1998
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.188.10.1785